First of all, did it work? Did you almost believe for 1.21 seconds that George Clooney might be Kilmering his career by voicing a car? You did, didn't you? Cool. The real story, a rumor that is flitting around the internets, is that Cloons is in talks to star in and possibly direct a biopic of automotive engineer and executive John DeLorean, best known for developing the DeLorean DMC-12 sports car (which can be seen at the top of the page. . .not needing any roads).
At first glance this seemed, to me, to be a terrible idea. Clooney is charismatic as hell, sure, but the last car engineering biopic I remember seeing was Tucker: The Man and His Dream with Jeff Bridges and the most exciting part of that 110 minutes was when they discovered seat belts. (Full disclosure, I did not see that movie where Greg Kinnear invents the windshield wiper. . .mostly because it looked bo-o-o-oring)
After some assiduous research, of the caliber you've come to expect in a Pajiba article (a.k.a. lazy wikipedia-ing), I found out John DeLorean was arrested in 1982 for drug-trafficking and that he allegedly turned to drug-trafficking in order to rescue his company from financial ruin. This is great, meaty, dramatic stuff and now I'm envisioning a dramatic car/helicopter confrontation, à la the end of Goodfellas. Replace a coked-up Ray Liotta with a coked-up Clooney and get the DeLoreans involved. . .possibly flying. . .cinemagical!
In terms of the casting choice of Cloons, well, I can see it. He and DeLorean both have a certain je ne sais eyebrow about them.
George "Silver Fox" Clooney
John "Snow Leopard" DeLorean
Though, clearly, this role belongs to character actor Milo O'Shea. Look at the eyebrows and tell me it's not true.